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Benno Weigmann Selected Research

Oxazolone

11/2022Label-Free Characterization and Quantification of Mucosal Inflammation in Common Murine Colitis Models With Multiphoton Imaging.
1/2020The JAK1/3 inhibitor tofacitinib suppresses T cell homing and activation in chronic intestinal inflammation.
7/2017Chemically induced mouse models of acute and chronic intestinal inflammation.
1/2017Rectal Delivery of a DNAzyme That Specifically Blocks the Transcription Factor GATA3 and Reduces Colitis in Mice.
1/2017Activation of Epithelial Signal Transducer and Activator of Transcription 1 by Interleukin 28 Controls Mucosal Healing in Mice With Colitis and Is Increased in Mucosa of Patients With Inflammatory Bowel Disease.
1/2016Oxazolone-Induced Colitis as a Model of Th2 Immune Responses in the Intestinal Mucosa.
7/2014TH9 cells that express the transcription factor PU.1 drive T cell-mediated colitis via IL-9 receptor signaling in intestinal epithelial cells.
9/2009IRF4 selectively controls cytokine gene expression in chronic intestinal inflammation.
9/2008The transcription factor NFATc2 controls IL-6-dependent T cell activation in experimental colitis.
7/2008The transcription factor IFN regulatory factor-4 controls experimental colitis in mice via T cell-derived IL-6.
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Benno Weigmann Research Topics

Disease

25Colitis
12/2022 - 09/2004
21Inflammation (Inflammations)
10/2021 - 01/2007
11Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
11/2022 - 09/2004
8Ulcerative Colitis
10/2021 - 01/2005
7Crohn Disease (Crohn's Disease)
01/2019 - 09/2004
5Type 1 Diabetes Mellitus (Autoimmune Diabetes)
12/2019 - 07/2011
4Neoplasms (Cancer)
12/2022 - 12/2010
4Colonic Neoplasms (Colon Cancer)
01/2017 - 12/2010
2Colorectal Neoplasms (Colorectal Cancer)
12/2022 - 09/2012
2Pneumonia (Pneumonitis)
10/2021 - 01/2019
2Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome)
10/2021 - 07/2015
2Colitis-Associated Neoplasms
01/2017 - 12/2010
2Autoimmune Diseases (Autoimmune Disease)
01/2016 - 12/2002
2Hyperglycemia
02/2014 - 08/2012
1Neointima
01/2022
1Arteriosclerosis
01/2022
1Seasonal Allergic Rhinitis (Hay Fever)
10/2021
1Drug Hypersensitivity (Drug Allergy)
01/2021
1Pruritus (Itching)
01/2021
1Pain (Aches)
01/2021
1Neoplasm Metastasis (Metastasis)
01/2020
1Lung Neoplasms (Lung Cancer)
01/2020
1Flushing
03/2019
1Porcine Reproductive and Respiratory Syndrome (PRRS)
01/2019
1Arthritis (Polyarthritis)
08/2017
1Hypersensitivity (Allergy)
04/2012

Drug/Important Bio-Agent (IBA)

17CytokinesIBA
10/2021 - 01/2005
11OxazoloneIBA
11/2022 - 01/2007
10Interleukin-6 (Interleukin 6)IBA
12/2022 - 07/2008
8Interleukin-9 (Interleukin 9)IBA
12/2022 - 07/2014
7InterleukinsIBA
08/2017 - 07/2009
6AllergensIBA
10/2021 - 07/2006
6Transcription Factors (Transcription Factor)IBA
01/2017 - 12/2002
5Proteins (Proteins, Gene)FDA Link
01/2022 - 01/2007
4Immunoglobulin E (IgE)IBA
10/2021 - 04/2012
4Insulin (Novolin)FDA Link
07/2017 - 07/2011
4HaptensIBA
07/2017 - 01/2007
3Dextran SulfateIBA
11/2022 - 01/2017
3Interleukin-17 (Interleukin 17)IBA
01/2020 - 06/2011
3Indicators and Reagents (Reagents)IBA
07/2017 - 01/2007
3Sulfonic AcidsIBA
07/2017 - 01/2007
3Interleukin-4 (Interleukin 4)IBA
01/2017 - 09/2004
2FlavonoidsIBA
01/2022 - 02/2018
2Cyclosporine (Ciclosporin)FDA LinkGeneric
10/2021 - 02/2015
2Pharmaceutical PreparationsIBA
01/2021 - 03/2019
2LigandsIBA
01/2021 - 01/2017
2Interleukin-5 (Interleukin 5)IBA
01/2020 - 01/2017
2Interleukin-13IBA
01/2020 - 01/2017
2AntigensIBA
07/2017 - 01/2007
2Phenobarbital (Luminal)FDA Link
07/2017 - 01/2007
2Interleukin-23 (Interleukin 23)IBA
01/2017 - 09/2008
2Messenger RNA (mRNA)IBA
01/2017 - 09/2009
2AcidsIBA
01/2017 - 01/2015
2FibrinIBA
07/2015 - 04/2012
2NFATC Transcription FactorsIBA
09/2012 - 09/2008
2Interferon Regulatory FactorsIBA
06/2011 - 09/2009
2sodium sulfate (sodium bisulfate)FDA LinkGeneric
07/2009 - 01/2007
2Dextrans (Dextran)FDA Link
07/2009 - 01/2007
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
01/2022
1Tec protein-tyrosine kinaseIBA
10/2021
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
01/2021
1Neutralizing AntibodiesIBA
01/2020
1Conditioned Culture MediaIBA
01/2020
1tofacitinibIBA
01/2020
1AutoantibodiesIBA
12/2019
1NucleotidesIBA
01/2019
1Lysine (L-Lysine)FDA Link
01/2019
1ZeinIBA
01/2019
1Deubiquitinating EnzymesIBA
01/2019
1NLR ProteinsIBA
01/2019
1Omalizumab (Xolair)FDA Link
01/2019
1Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA
01/2019
1Pattern Recognition ReceptorsIBA
01/2019
1ApigeninIBA
02/2018
1epigallocatechin gallate (epigallocatechin-3-gallate)IBA
02/2018
1Peptides (Polypeptides)IBA
07/2017
1STAT1 Transcription FactorIBA
01/2017
1Type II Tumor Necrosis Factor ReceptorsIBA
01/2017
1Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
01/2017
1Interleukin-12 (IL 12)IBA
01/2017
1NADPH Oxidases (NAD(P)H oxidase)IBA
01/2017
1Catalytic DNA (Deoxyribozyme)IBA
01/2017
1InterferonsIBA
01/2017
1Interleukin-23 Subunit p19IBA
01/2017
1Toll-Like Receptor 9IBA
01/2017
1Interferon Regulatory Factor-3 (Interferon Regulatory Factor 3)IBA
01/2017
1Budesonide (Pulmicort)FDA LinkGeneric
05/2016
12,4,6-trinitro-benzenesulfonic acidIBA
01/2016
1Interleukin-10 (Interleukin 10)IBA
01/2016
1Glycoproteins (Glycoprotein)IBA
07/2015
1Interleukin-9 Receptors (Interleukin 9 Receptor)IBA
07/2014
1proto-oncogene protein Spi-1IBA
07/2014
1IgE Receptors (Fc epsilon RI)IBA
04/2012
1Histamine (Histamine Dihydrochloride)FDA Link
04/2012
1Platelet Activating FactorIBA
04/2012

Therapy/Procedure

6Therapeutics
12/2022 - 01/2007
3Transplantation
01/2022 - 07/2008
2Immunotherapy
01/2016 - 08/2012
1Topical Administration
07/2017
1Injections
01/2017